PC Lock Ups/Debugger Error

We are having problems with new DEll Optiplex GX150 and GX240’s. Users are getting the following error, whenever, no pattern or particular software.

Error – This program cannot be closed. If it is being debugged, pelase resume it or close thedebugger first. OK.

After error message, the workstation completely freezes and has to be powered off and on.

Thanks for anyone’s help on this. Kathy