Problems with Lotus Notes

I’m experiencing a few problems with Lotus Notes and wondered if anyone could give me hand.
Some Applications within Notes, specifically:
“Send Newsletter”
“Out of Office”
“Callender Profile”
Are not functioning properly.
When i printed out a Notes Log, I get the following error messages.
“SchedMgr: Error processing calendar profile document (NoteID:NT00002102)in database..”
“AMrg: Agent ‘ProcessOutOfOffice’ in…is not set to run on this system
Has Anyone got a solution???