You could rename Otuneup.exe.
The Office File Optimizer operates on Windows 95 and 98. The wizard is not designed to run on Windows NT. The utility runs the first time Windows is started after you install Office 2000 and then runs automatically as needed. When Windows starts it compares the order of the optimized file list stored in the Windows registry, to the physical location of Office files on your hard disk. If the location of the files has changed, the Office File Optimizer is started.
You can run the Office File Optimizer manually by running Otuneup.exe located in the folder in which you installed Office. By default this folder is C:\Program files\Microsoft Office\Office. You can prevent the utility from running by clicking to clear the Run checks in the future check box in the Microsoft Office 2000 File Optimizer dialog box.