changed ip address on Citrix Metaframe

We have Metframe 1.0 feature release 3.0, Windows 2003 server. We have changed the ip address on the server and can not get into the Nfuse applications. Everything worked fine until we changed the ip address on the servers Nic. I can get into the server with the ICA client. I can login into the server on the Nfuse side but I can not use any of the applications. Does anyone have a clue why?