It means that someone (either in the past or presently) is using your Exchange Server as a SPAM relay site. There are several organizations that collect information on such sites and compile "black hole" or "real-time black hole" (RTB) lists of such sites for distribution to subscribers. These lists are used as filters to prevent SPAM from overloading their Exchange Servers.
To ensure your server isn't currently be used as an open-relay server, open the Relay Restrictions dialog box for your SMTP virtual server. Make sure the "All except the list below" box is NOT checked (this is the default). If it isn't, your server may be on the list from the past and never got removed. If it is checked, your server is (probably) presently beused by others for nefarious purposes
To see if your site is listed, check with "www.mail-abuse.org" or "www.abuse.net" (2 of the more common RTB lists. You will also find info on how to get your server removed from the list (make sure you have blocked relay first).
Hope this helps.