External F: HDD Sanitisation while continuing to work in C: Win 7

By ozdennisb ·
What is the risk to data of formatting External F: Drive while working on C Drive Office 7. Data is stored on an external E: Drive. The Backup onto F: keeps malfunctioning. Is there any option other than a diskwipe of F: and then a complete new back-up of all data to it?

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