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Are you using a Logitech mouse? There is an incompatibility between Office 2000 and the Logitech Enhanced Control Center and the Logitech mouse driver version 6.42.
See Microsoft Support article #Q240325 for details if this is the case.
http://support.microsoft.com/support/kb/articles/Q240/3/25.ASP
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Usually this kind of problem is caused by a mouse problem. Either the software is faulty, or you have conflicts in IRQ or I/O addresses.

I hope this helps some.

Yip, I've heard of that problem too.
Have been surfing for tips, but no info as of yet.
Help greatly appreciated.
NOTE: After reinstalling Office/Excel the problem does disappear for a short while, then all of a sudden it comes back. No logitech mouse here either. Trackpoint on a laptop...
OS: Win2K

Are you using a scrolling mouse? If so and the scroll button gets stuck it will select all cells pointed to. Just double click the scroll button and it's okay. I am an instructor and this happens a lot in my beginning classes. Hope this is your problem.

Are you using a scrolling mouse? If so and the scroll button gets stuck it will select all cells pointed to. Just double click the scroll button and it's okay. I am an instructor and this happens a lot in my beginning classes. Hope this is your problem.

You could try the following steps, it could well be a resource issue.

1. Reduce Hardware accelleration for the Graphic card:
Start ->Control Panel -> Display Properties -> Settings -> Advanced -> Troubleshooting -> Reduce the slider a coupleof notches.

2. Check Device manager for resource conflicts with the mouse.

3. Remove the mouse drivers from Device Manager, it will be detected and reinstalled on bootup.

4. Remove the display adapter drivers from Device Manager, it will be detected and reinstalled on bootup.