Microsoft Exchange Server - Multiple dom

Yes you can. Have the Mx records point to the ip of your exchange server. On the connections tab, go to the internet mail connector go to the routing tab, choose reroute incoming mail, click add, type in the domain name i.e mymail.com and choose should be accepted as inbound. New mail with this domain name should be routed to users that have been setup with smtp addresses for this domain. Don't need a second server.

answer 1 will help you in exchange 5.5. My answer is if your running exchange 2000.

Update the default recipient policy in exchange to include the @newdomain.com domain. Your exchange server will reject emails if you don't do this.
Go to theexchange system manager, recipients, recipients policies, default policy, properties, email tab, new, smtp address, under address field put @newdomain.com, hit ok, put a checkbox on it, select it, set as primary, hit ok, hit yes to apply to all users.

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