…especially in the NTFS world. While MS has done an excellent job of making NTFS reliable and stable, disk corruption happens. It will eventually happen to any filesystem.
Every try running CHKDSK on a 2TB filesystem? How about one with 1 million files? Be prepared to have your data off-line for 8-12 hours (or longer on SATA) and pray you don’t end up going to tape for some of it.
MS has taken a hint from the UNIX world with mount points. Smaller volumes brought together with mount points is typically a better way to go and all your data does not end up in one big basket.
Obviously, no one solution fits all and sometimes you just need 10 TB in one filesystem. If that is you, maybe NTFS is not your best choice of filesystem, but it will work.