Any Idea what could be wrong?

Problem: User is logged into their desktop, is running XPP; while in our MIS software, trys to run a report, nothing comes up but a blank repport, user then logs into a neighboring desktop, run software, runs report and everything is fine, so then I log into the users desktop as the admin, run mis software run, run the report and it looks fine, then I have user log back into their desktop again and try it, the report comes out blank.

I have tried to uninstall and re-install the software, same result, so I believe that it is not the software, user error or netowrk connection, I been thinking that it is posible that the users profile on that desktop is corrupted, anyone care to give me an idea what is wrong.