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There is nothing that says you can’t. However, you will have to work within the limitations of UTP, i.e.
1. 100m cable segment length between network devices capable of retransmitting/amplifying data signals and/or end nodes.
2. Subject to EMI (electro-magnetic interference), which will dictate where you can or can’t run backbone cabling.
For these reasons (and the reasons mentioned in Answer 1), unless you have a very small backbone you wish to construct, you are usually better off with fiber.