Do what I do for myself, the Plant Manager, Chief Accountant, and a guy with Maintenance/Spare Parts software: use Second Copy 2000.
I think someone on this list suggested it. I went and tried this out some two months back and now cannot imagine living without. In short, you set up a backup routine (anywhere from every minute to every other year), style (copy/synchro/compress/archive, with variations), source and target, and forget the whole thing. If one of your files is open, a feminine voice tells you so and you have 30 secs to close it, plenty enough.
This is shareware with one-month free trial (but it doesn't self-destruct after that) and healthy reductions for multi-user licenses (I bought 5 and paid for 4, for instance).
I was forced to restore some lost files already and believe me, there is NOTHING simpler or quicker, you just copy the needed files back where they belong, period.
Do give it a try.
http://www.centered.com/
Oh yes, you will have to have a single central backup depot, so to speak, that you DDR/DAT/whatever regularly. But THIS I think you've had for a while :-)))
regs,
wyrm