Desktop Security

Most Desktop Security programs allow you decide which programs can be used or if you may use the cdrom or not.

I need a program or set of programs or configuration that will allow me to create a list of files that only those files may be run and no others, and access to certain folders and all their files and no others. This list may also include files that are on removable drives.
You should not be able to bypass it by killing the program with Ctrl Alt Del and if you uninstall it you stillwont be able to run the “other files”, or you can’t uninstall it.
I need this for Win 95/98/ME and Win 2000/XP.
I will accept more than one answer, all that work.