Excel Issue

When I try & open an Excel file Excel gives me this error message saying, “C:\Program Files\Business Functions\ BUSFUN.XLA could not be found. check the spelling of the file name to make sure it is correct, etc…” This isn’t the name of my file nor is the place where I am opening it from. If I say ok to the error message, it will still give me full access to the file but I still continue to get that error message every time I open the file up again.

Help?