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exe file cannot open

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i have notebook windows 2000 sp2,the system boot normal but cannot open file which have .exe .I thougth virus attack the system and used trendmicro DCS and sysclean,also not restore back.I also try restore used original cd win2000 repair task and also not work.Please anybody can help me,thanks a lot.

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by valis

what particular .exe file, and what if any error messages do you get?

by sabli

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All file which used executable extension file cannot open and error message appear cannot find file or being used by another program.

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