Our backup solution at the moment anyhow (we are looking into improvments and changes, possibly a NAS solution to augment our storage needs) is traditional tape backup. We have a Dell Powervault (autoloader) and our software is Veritas Backup Exec 9.1. our backup volume is very low compared to some of the companies you guys probably work for...but we have about 85 GB that is currently backed up from 2 servers.
Once we got the initial config settings out of the way, we can't be more please with the solution (except our autoloader isn't the fastest)..its pretty much a hands free operation. We have it email us any problems/errors/alerts even at home we get the alerts. Which I like.
We do an incremental during the week/ full backup on weekends strategy. We rotate copies of course, of which a copy is stored in our secured server room (with fire supression system, temperature controlled, etc.) this copy is in a fire safe. Then myself and the other engineer that works with me share responsibilities on taking an emergency copy (we label it the 911 copy) home with us.
A little bit of time consumed in making two copies of the masters , yeah I know..but it makes us feel warm and fuzzy with regards to security of our data.