This is an odd error that I have come across. I am creating a form that users can use to submit some text with an optional photo. My first trial of this form threw an Access denied error when run in IE, at the time I did not attempt to run it in Firefox. On my private test server where I was testing the form, I set the permissions for the ASP.NET account (its written in ASP.NET and some C#) to full access as it needs to modify a text file and save the photos to the server. It works perfectly in IE, but when run in Firefox I get the Access to the path C:\