Hi, I think Dansguardian only runs on Linux, with Squid acting as the proxy server and Dansguarding providing the URL blocking. I just set this up on SuSe Pro 9.1 and am going to set it up on SuSe 9 Enterprise Server next. I'm not sure there is solution to integrating is with ISA. However, Dansguardian is free (for non-profits) and very inexpensive if you are a for profit. All the third party filters for ISA (IE: Surfcontrol, Websense?) are very expensive by comparison.
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ISA 2004 working with DansGuardian