First try to have that developer log in and disconnect the mapped drives. If the developer is no longer available, then you will need to log on as an administrator, and find and load the User Hive for the developer in the REGEDT32 Registry Editor.You have to use this one because REGEDIT will not allow you to load other hives. (Be VERY careful whenever you have to edit the registry directly! One bad keystroke or mouse-click can mean disaster.)
Assuming this is NT 4.0 server, select Run from the Start menu and type REGEDT32, and when it opens minimize all your windows except the HKEY_LOCAL_MACHINE window. Then choose Load Hive from the Registry Menu. Navigate to your NT Profiles directory to find the profile for the developer, for example, C:\WINNT\Profiles\DeveloperUserName, and choose Ntuser.dat and click on the Open button. When Asked for a Key name type something like HKEY_Developer_User and hit enter. The new Key will appear in your active window. Double-click on the key to expand it, and you'll see a Network Key. Double-click on that key, and you should see a list of all the mapped drives for that user. You can then click on them one at a time and hit the delete key, and choose Yes when asked if you want to delete the key. You can then unload the hive, and then exit REGEDT32.
Log off and log in as you normally were, and hopefully all those mapped drives will be gone.
Good luck, and again, be very careful. I hope this helps.