NTLDR is missing, press any to continue

There are two hd in this machine. The C:\ is a SCSI drive, bios enabled. The D:\ is IDE. Fresh install of Windows 2000 on C:\ drive.
Everything was great…even after the service packs. But, when I plugged in the IDE drive, I get a “NTLDR is missing Press any key to continue.” If I remove the D:\ drive, this is not an issue. What’s going on? How do I get rid of this problem?