First, check for, and install any updated drivers for your motherboard / chipset. These often include improved IRQ steering over the default windows drivers.
If that doesn't take care of things:
Open up device manager.
Remove any devices that you do not use (COMM Ports)
Expand the system devices branch.
Select PCI Bus.
In the properties box, click on the IRQ steering tab.
Disable IRQ steering.
Apply and close the open windows.
Restart your system.
Enter BIOS setup.
Disable anyunused ports that you removed from device manager.
Under PCI / PNP, enable update configuration / ECPI.
Save and exit setup.
Complete the boot process.
Windows should automatically re-assign IRQs to avoid conflicts.
Shut down and boot up 2 more times.
Verify that the IRQ conflicts are corrected.
Go back into device manager, and re-enable IRQ steering.