User Accounts – Office 2000

Currently running a NT4 network, one of the PC’s connected to the network is a Windows 2000 desktop. In the past it has always been logged on as the same person, a different person has attempted onto the PC, and a user account for the PC was set up. However once they were on the PC none of the Office 2000 products could be accessed, I got error messages that s/w needed to be reinstalled, have been on the Microsoft site, and followed their suggestions but still to no avail, I am sharing the Start Menu and Programs folder.
Just wondering does anyone out there have any suggestions, or is it possible to turn off the user profiles for the PC??

Thanks in advance.