win - me profiles

Matt,
The username and passwords need to match the ones on server.
So if you have account John Doe password:secret
You need to setup ME profile as John Doe with a password of secret
As far as roaming ? do mean desktops settings or access rights because with above the access will roam wherever they login.
Desktop settings are a little tricky, you have to setup a shared dir for profiles and you have to do a special network setup while installing the workstations. To be honest I haven't heardof network setup for Windows for a long time so I am not sure if you can do a network setup of ME (do a setup /? and it will give you parameters you can use during setup)