Win98 can’t detect Serial Mouse

I have seen this before under Win98. Serial Mice stop working. The system I am working on I’ve worked on before with the same problem. To resolve the issue before, I had installed a Serial Adapter Card which allowed Windows to recognize the Serial Mouse. Now I’m back to the same problem. I had research the issue using MS Knowledge Base, and preformed what I could find, but I still get the error: “Windows did not detect a mouse attached to the Computer. You can safely attach a Serial Mouse now.”
FYI, I’ve tried uninstalling and reinstalling all ports, Mouse drivers, and even editing the Registry. I’ve tried using different mice. I hoping that someone has encountered this same problem and has found the answer.
Also note that CMOS settings are good.

Thank you!