First mouse click not recognised

Hi

A friend has a computer running Win98SE, with 32MB RAM, and 100’s of MB of free space. A standard microsoft compatible serial mouse is attached. When an OK, Close, Cancel button is clicked nothing happens. When the button is clicked a second time the requested action is performed. If a CD is inserted, the autoplay feature will not start until a blank area of the desktop has been clicked.

Any help would be appreciated.

Thanks