You can install Symantec Antivirus Corporate version that can be installed to client computers from the server. Once installed you can schedule the frequency and that times for automatic scanning as well as perfrom on demand manual scans. Virus definitions can also be updated automatically. The nice part about the corporate version is that you can have a overall view of the status of the definition files, the dates of the most recent scans as well as an overview of viruses detected and quarantined.
With version 10 of symantec corporate, they have a fully certified .msi file, the only custom thing you need to do to the .msi is add a force reboot. Then create a GPO under software installation for machine settings.
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