E-business is one of the most important business forms. E-business allows organizations to do their business, internally and externally, efficiently and effectively with relatively low costs. Unfortunately, e-business faces several risks which can affect its processes. Additionally, e-business risks are divided into internal and external risks. The paper determines numerous guidelines to deal with the e-business risks. Proposed guidelines represent an effective method to minimize the effect of risk or to avoid it. Presented guidelines are suitable for most types of organizations when used properly and effectively.